Castro Valley High School is a comprehensive high school providing a wide variety of course offerings, including Advanced, Honors, and Advanced Placement courses. These courses include Advanced Sophomore English, AP Calculus AB and BC, Honors American Literature, AP Statistics, AP English Literature, AP Computer Science, AP United States History, AP Economics, AP Biology, AP European History, Honors Chemistry, AP Studio Art, AP Chemistry, AP Art History, Honors Physics, Honors Chamber Orchestra, AP Environmental Science, Honors American Sign Language, AP Spanish, AP French, AP German, and AP Japanese.
Castro Valley High is the only high school in the United States to offer Honors American Sign Language.